Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 12/20 | 0.68 |
| ▸ | FAP | Q12884 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17254216 | 1.00 | PREP (0.68) | PREPFAPF2 | |
| SCHEMBL13377231 | 1.00 | PREP (0.68) | PREPFAPF2 | |
| SCHEMBL13377217 | 1.00 | PREP (0.68) | PREPFAPF2 | |
| SCHEMBL10022741 | 1.00 | PREP (0.68) | PREPFAPF2 | |
| Hydrochloric Acid SCHEMBL31758287 | 0.99 | PREP (0.67) | PREPFAPF2 | |
| SCHEMBL10022737 | 0.91 | PREP (0.67) | PREPFAPF2 | |
| SCHEMBL10022739 | 0.91 | PREP (0.67) | PREPFAPF2 | |
| SCHEMBL8285593 | 0.90 | PREP (0.66) | PREPFAPF2 | |
| SCHEMBL13417171 | 0.90 | PREP (0.66) | PREPFAPF2 | |
| SCHEMBL7889613 | 0.90 | PREP (0.66) | PREPFAPF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100098633-A1 | SELECTIVE SEPRASE INHIBITORS | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2010-04-22 | — | — | US | disclosed |
| US-20100098633-A1 | SELECTIVE SEPRASE INHIBITORS | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2010-04-22 | — | — | US | disclosed |
| WO-2010036814-A1 | SELECTIVE SEPRASE INHIBITORS | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2010-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100098633-A1 | SELECTIVE SEPRASE INHIBITORS | SLC6A7, DNPEP, PREP | PREP 3/4885FAP 4/4885F2 3391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.