Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 5/20 | 0.39 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL743013 | 0.82 | EPHX1 (0.51) | EPHX1HDAC4HDAC1HDAC6GAA | |
| SCHEMBL500289 | 0.82 | EPHX1 (0.51) | EPHX1HDAC4HDAC1HDAC6GAA | |
| Hydrochloric Acid SCHEMBL16007752 | 0.82 | GAA (0.54) | EPHX1HDAC4HDAC1HDAC6GAA | |
| SCHEMBL7939704 | 0.80 | EPHX1 (0.46) | EPHX1HDAC4HDAC1HDAC6GAA | |
| SCHEMBL18361542 | 0.79 | MEN1 (0.44) | EPHX1GAAMAOBCTSKCTSS | |
| SCHEMBL7729067 | 0.77 | BTK (0.38) | EPHX1HDAC4HDAC1HDAC6GAA | |
| SCHEMBL7728349 | 0.77 | BTK (0.38) | EPHX1HDAC4HDAC1HDAC6GAA | |
| SCHEMBL7728341 | 0.77 | BTK (0.38) | EPHX1HDAC4HDAC1HDAC6GAA | |
| SCHEMBL7727553 | 0.77 | BTK (0.38) | EPHX1HDAC4HDAC1HDAC6GAA | |
| SCHEMBL5126670 | 0.75 | KMT2A (0.53) | EPHX1HDAC4HDAC1HDAC6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3788031-B1 | DIPEPTIDYL KETOAMIDE META-METHOXYPHENYL DERIVATIVES AND USES THEREOF | LANDSTEINER GENMED S L (ES) | 2023-09-27 | — | — | EP | disclosed |
| EP-3564211-A1 | DIPEPTIDYL KETOAMIDE META-METHOXYPHENYL DERIVATIVES AND USES THEREOF | LANDSTEINER GENMED, S.L. (ES) | 2019-11-06 | — | — | EP | disclosed |
| WO-2010068714-A2 | DEUTERATED COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS | SCHERING CORPORATION (US) | 2010-06-17 | — | — | WO | disclosed |
| EP-1737821-B1 | 3,4-(CYCLOPENTYL)-FUSED PROLINE COMPOUNDS AS INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORP (US) | 2009-08-05 | — | — | EP | disclosed |