Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | MANBA | O00462 | 1/20 | 0.41 |
| ▸ | IDUA | P35475 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 4/20 | 0.31 |
| ▸ | NAAA | Q02083 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13176616 | 0.91 | HIF1A (0.46) | HIF1ALMNATHRBDNMT1CTDSP1 | |
| SCHEMBL10110534 | 0.79 | MEN1 (0.31) | — | |
| SCHEMBL13120130 | 0.79 | HIF1A (0.35) | HIF1ALMNATHRBDNMT1CTDSP1 | |
| SCHEMBL13105442 | 0.79 | HIF1A (0.35) | HIF1ALMNATHRBDNMT1CTDSP1 | |
| SCHEMBL12750412 | 0.76 | LMNA (0.68) | HIF1ALMNATHRBDNMT1CTDSP1 | |
| SCHEMBL13176821 | 0.76 | LMNA (0.68) | HIF1ALMNATHRBDNMT1CTDSP1 | |
| SCHEMBL12833579 | 0.76 | HIF1A (0.34) | HIF1ALMNATHRBDNMT1CTDSP1 | |
| SCHEMBL10111215 | 0.75 | HIF1A (0.35) | HIF1ALMNATHRBMANBACYP2C19 | |
| SCHEMBL18418394 | 0.75 | HIF1A (0.33) | HIF1ALMNATHRBDNMT1CTDSP1 | |
| SCHEMBL18418395 | 0.75 | HIF1A (0.33) | HIF1ALMNATHRBDNMT1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245810-B1 | ANTITUMOR, ANTICARCINOGENIC AGENTS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0617009-B1 | NOVEL AMINO ACID DERIVATIVE | ZAIDAN HOJIN BISEIBUTSU (JP) | 1999-09-08 | — | — | EP | disclosed |
| US-5798387-A | IMMUNOMODULATOR AND AN ANTITUMOR AGENT OR HEMATOPOIETIC STEM CELL AMPLIFIER | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1998-08-25 | — | — | US | disclosed |
| EP-0617009-A1 | NOVEL AMINO ACID DERIVATIVE | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1994-09-28 | — | — | EP | disclosed |