Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL451924 | 0.86 | HDAC3 (0.54) | HDAC3CA12CA1IDO1ALOX15 | |
| SCHEMBL28641832 | 0.81 | HDAC3 (0.58) | HDAC3CA12CA1IDO1ALOX15 | |
| SCHEMBL3658195 | 0.79 | GAA (0.48) | HDAC3CA12CA1IDO1ALOX15 | |
| SCHEMBL23493515 | 0.79 | TSHR (0.50) | HDAC3CA12CA1IDO1ALOX15 | |
| SCHEMBL30480946 | 0.78 | HDAC1 (0.65) | HDAC3HDAC1HDAC2HDAC6GAA | |
| SCHEMBL23778469 | 0.78 | HDAC1 (0.65) | HDAC3HDAC1HDAC2HDAC6GAA | |
| SCHEMBL10336633 | 0.77 | SMN1; SMN2 (0.46) | HDAC3CA12CA1IDO1ALOX15 | |
| SCHEMBL15065492 | 0.75 | SMN1; SMN2 (0.45) | HDAC3CA12CA1IDO1ALOX15 | |
| SCHEMBL4710827 | 0.74 | HDAC1 (0.70) | HDAC3CA12CA1IDO1ALOX15 | |
| SCHEMBL6680009 | 0.74 | KMT2A (0.49) | GAAMEN1KMT2APOLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111153931-A | 2-pyridine methane imine tin (II) compound and preparation method and application thereof | 山西大学 | 2020-05-15 | — | — | CN | claimed |
| EP-0034394-B1 | PROCESS FOR THE PREPARATION OF 3'-BROMOSUBSTITUTED DEACETOXYCEPHALOSPORANIC ACID SULPHOXIDE DERIVATIVES | GIST-BROCADES N.V. (NL) | 1984-08-01 | — | — | EP | claimed |
| US-4366315-A | Process for preparing 3'bromo-desacetoxycephalosporanic acid sulfoxide compounds | GIST-BROCADES N.V. (NL) | 1982-12-28 | — | — | US | claimed |
| EP-0034394-A2 | Process for the preparation of 3'-bromosubstituted deacetoxycephalosporanic acid sulphoxide derivatives | GIST-BROCADES N.V. (NL) | 1981-08-26 | — | — | EP | claimed |
| US-4014873-A | Process for the production of 7-acylamidocephalosporins | MERCK & CO., INC. (US) | 1977-03-29 | — | — | US | claimed |
| CN-112939836-B | Beta-lactam compound and preparation method thereof | 河南大学 | 2022-11-18 | — | — | CN | disclosed |
| CN-112939836-A | Beta-lactam compound and preparation method thereof | 河南大学 | 2021-06-11 | — | — | CN | disclosed |
| CN-101888991-A | Retinoid prodrug compound | RES FOUND ITSUU LAB | 2010-11-17 | — | — | CN | disclosed |
| CN-100415750-C | Fungicides for the control of take-all disease of plants | MONSANTO CO (US) | 2008-09-03 | — | — | CN | disclosed |
| CN-101243061-A | Processes for the preparation of docetaxel | UNIV FLORIDA STATE RES FOUND (US) | 2008-08-13 | — | — | CN | disclosed |
| CN-101243060-A | Processes for the preparation of paclitaxel | UNIV FLORIDA STATE RES FOUND (US) | 2008-08-13 | — | — | CN | disclosed |
| CN-1772749-A | Fungicides for the control of take-all disease of plants | MONSANTO CO (US) | 2006-05-17 | — | — | CN | disclosed |
| US-4366315-A | Process for preparing 3'bromo-desacetoxycephalosporanic acid sulfoxide compounds | GIST-BROCADES N.V. (NL) | 1982-12-28 | — | — | US | disclosed |
| US-4330535-A | Fungicidal azolyl-silyl-glycol ethers, their use for combating fungi, and agents therefor | BASF AKTIENGESELLSCHAFT (DE) | 1982-05-18 | — | — | US | disclosed |
| EP-0043630-A2 | Improved process for the silylation of organic compounds with 1,1,1-trimethyl-N-(trimethylsilyl)silanamine by means of catalysis with certain nitrogen containing compounds | GIST-BROCADES N.V. (NL) | 1982-01-13 | — | — | EP | disclosed |
| EP-0034394-A2 | Process for the preparation of 3'-bromosubstituted deacetoxycephalosporanic acid sulphoxide derivatives | GIST-BROCADES N.V. (NL) | 1981-08-26 | — | — | EP | disclosed |
| EP-0031962-A2 | Fungicidal azolyl-silyl-glycol ethers, their preparation, their use to combat fungi and composition therefor | BASF Aktiengesellschaft (DE) | 1981-07-15 | — | — | EP | disclosed |
| US-4107432-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1978-08-15 | — | — | US | disclosed |
| US-4058661-A | 7-Diacyl cephalosporins | MERCK & CO., INC. (US) | 1977-11-15 | — | — | US | disclosed |
| US-4014873-A | Process for the production of 7-acylamidocephalosporins | MERCK & CO., INC. (US) | 1977-03-29 | — | — | US | disclosed |