Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.55 |
| ▸ | F7 | P08709 | 1/20 | 0.53 |
| ▸ | F3 | P13726 | 1/20 | 0.53 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30480946 | 1.00 | HDAC1 (0.65) | HDAC1HDAC6LMNATHRBHIF1A | |
| SCHEMBL2988299 | 0.81 | HDAC1 (0.65) | HDAC1HDAC6LMNATHRBHIF1A | |
| SCHEMBL3821696 | 0.81 | HDAC1 (0.69) | HDAC1HDAC6LMNATHRBHIF1A | |
| Nicotinyl Methylamide SCHEMBL28560459 | 0.81 | HDAC1 (0.69) | HDAC1HDAC6LMNATHRBHIF1A | |
| Nicotinyl Methylamide SCHEMBL30664356 | 0.81 | HDAC1 (0.69) | HDAC1HDAC6LMNATHRBHIF1A | |
| Nicotinyl Methylamide SCHEMBL129458 | 0.81 | HDAC1 (0.69) | HDAC1HDAC6LMNATHRBHIF1A | |
| SCHEMBL2000041 | 0.80 | HDAC1 (0.74) | HDAC1HDAC6LMNATHRBHIF1A | |
| SCHEMBL5361880 | 0.80 | HDAC1 (0.74) | HDAC1HDAC6LMNATHRBHIF1A | |
| Iodide SCHEMBL28221159 | 0.80 | HDAC1 (0.62) | HDAC1HDAC6LMNATHRBHIF1A | |
| Nicotinyl Methylamide SCHEMBL5528294 | 0.79 | HDAC1 (0.67) | HDAC1HDAC6LMNATHRBHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250127804-A1 | RIBOSE LINKERS AND CONJUGATES THEREOF | UNIVERSITY OF SOUTH ALABAMA | 2025-04-24 | — | — | US | disclosed |
| EP-4472993-A2 | RIBOSE LINKERS AND CONJUGATES THEREOF | Elysium Health, Inc. (US) | 2024-12-11 | — | — | EP | disclosed |
| CN-118632855-A | Ribose linker and conjugates thereof | 益力舒健康公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-118530963-A | Method for efficiently synthesizing beta-nicotinamide riboside in vitro and application thereof | 杭州微远生物科技有限公司 | 2024-08-23 | — | — | CN | disclosed |
| US-11767314-B2 | Bioenergetic nicotinic acid glycerol esters, compositions and methods of using same | CONOPCO, INC. (US) | 2023-09-26 | — | — | US | disclosed |
| WO-2023150667-A2 | RIBOSE LINKERS AND CONJUGATES THEREOF | ELYSIUM HEALTH INC. (US) | 2023-08-10 | — | — | WO | disclosed |
| WO-2023150667-A2 | RIBOSE LINKERS AND CONJUGATES THEREOF | ELYSIUM HEALTH INC. (US) | 2023-08-10 | — | — | WO | disclosed |
| CN-112955115-B | Bioenergy glyceryl nicotinate, compositions and methods of using the same | 联合利华知识产权控股有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-111909229-B | Preparation method of beta-nicotinamide riboside chloride | 福建瑞博奥科技有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-111647032-B | Synthesis method of beta-nicotinamide mononucleotide | 上海舒泽生物科技研究所 | 2023-02-24 | — | — | CN | disclosed |
| CN-112724180-B | Preparation method of beta-nicotinamide mononucleotide | 黄冈鲁班药业股份有限公司 | 2023-01-10 | — | — | CN | disclosed |
| US-20210380564-A1 | BIOENERGETIC NICOTINIC ACID GLYCEROL ESTERS, COMPOSITIONS AND METHODS OF USING SAME | CONOPCO, INC., D/B/A UNILEVER (US) | 2021-12-09 | — | — | US | disclosed |
| CN-113621004-A | Preparation method of beta-nicotinamide riboside chloride | 八叶草健康产业研究院(厦门)有限公司 | 2021-11-09 | — | — | CN | disclosed |
| EP-3873415-A1 | BIOENERGETIC NICOTINIC ACID GLYCEROL ESTERS, COMPOSITIONS AND METHODS OF USING SAME | UNILEVER GLOBAL IP LIMITED (GB) | 2021-09-08 | — | — | EP | disclosed |
| CN-112955115-A | Bioenergy glyceryl nicotinates, compositions and methods of using the same | 联合利华知识产权控股有限公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-112724180-A | Preparation method of beta-nicotinamide mononucleotide | 黄冈鲁班药业股份有限公司 | 2021-04-30 | — | — | CN | disclosed |
| CN-111909229-A | Preparation method of beta-nicotinamide riboside chloride | 福建瑞博奥科技有限公司 | 2020-11-10 | — | — | CN | disclosed |
| CN-111647032-A | Synthesis method of beta-nicotinamide mononucleotide | 上海舒泽生物科技研究所 | 2020-09-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767314-B2 | Bioenergetic nicotinic acid glycerol esters, compositions and methods of using same | PRKAG1, PRKAB1, PRKAG2 | HDAC1 1436/4885HDAC6 979/4885LMNA 2336/4885 |
| US-20210380564-A1 | BIOENERGETIC NICOTINIC ACID GLYCEROL ESTERS, COMPOSITIONS AND METHODS OF USING SAME | PRKAG1, PRKAB1, PRKAG2 | HDAC1 1436/4885HDAC6 979/4885LMNA 2336/4885 |
| US-20250127804-A1 | RIBOSE LINKERS AND CONJUGATES THEREOF | CD38, NQO1, PARP1 | HDAC1 155/4885HDAC6 202/4885LMNA 435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.