Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938399 | 1.00 | CCR5 (0.78) | CCR5 | |
| SCHEMBL7548513 | 0.88 | CCR5 (1.00) | CCR5 | |
| SCHEMBL7542220 | 0.81 | CCR5 (1.00) | CCR5 | |
| SCHEMBL7550208 | 0.81 | CCR5 (0.72) | CCR5 | |
| SCHEMBL7548515 | 0.81 | CCR5 (0.68) | CCR5 | |
| SCHEMBL7546503 | 0.76 | CCR5 (0.87) | CCR5 | |
| SCHEMBL7545273 | 0.75 | CCR5 (0.65) | CCR5 | |
| SCHEMBL7545278 | 0.75 | CCR5 (0.65) | CCR5 | |
| SCHEMBL5764111 | 0.74 | CCR5 (0.54) | CCR5 | |
| SCHEMBL7542224 | 0.74 | CCR5 (0.68) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248755-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS; AUTOIMMUNE DISEASES | MERCK & CO., INC. | 2001-06-19 | — | — | US | disclosed |