Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.75 |
| ▸ | MAPT | P10636 | 7/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12684775 | 0.88 | ALDH1A1 (0.61) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL12684769 | 0.86 | ALDH1A1 (0.58) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL12684776 | 0.86 | ALDH1A1 (0.58) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL7940000 | 0.85 | ALDH1A1 (0.57) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL15854533 | 0.85 | ALDH1A1 (0.57) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL15854531 | 0.85 | ALDH1A1 (0.64) | ALDH1A1MAPTKMT2AMEN1DCTPP1 | |
| SCHEMBL375759 | 0.84 | ALDH1A1 (0.71) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL12684773 | 0.83 | ALDH1A1 (0.65) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1842729 | 0.82 | ALDH1A1 (0.64) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL7937794 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MAPTKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2320897-B1 | COMPOSITIONS AND METHODS OF TREATING AMYLOID DISEASE | TREVENTIS CORP (US) | 2014-01-15 | — | — | EP | disclosed |
| WO-2010025375-A1 | COMPOSITIONS AND METHODS OF TREATING AMYLOID DISEASE | TREVENTIS CORPORATION (US) | 2010-03-04 | — | — | WO | disclosed |