SCHEMBL7938449

SCHEMBL7938449

CCCC[Sn](C=CC1CCC(NC(=O)OC(C)(C)C)(C(=O)OC)CC1)(CCCC)CCCC

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 1/20 0.31
ALDH1A1 P00352 1/20 0.30
KMT2A Q03164 1/20 0.30
MAPT P10636 1/20 0.30
PPIA P62937 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7926226 0.94
SCHEMBL7926228 0.89 MEN1 (0.30) KMT2A
SCHEMBL7934956 0.79 GHSR (0.36) GHSRALDH1A1KMT2A
SCHEMBL3375037 0.78 BTK (0.39) ALDH1A1KMT2A
SCHEMBL3375034 0.78 BTK (0.39) ALDH1A1KMT2A
SCHEMBL7934810 0.77 GHSR (0.33) GHSRALDH1A1KMT2A
SCHEMBL7935522 0.75 GHSR (0.37) GHSRALDH1A1KMT2A
SCHEMBL7936504 0.74 MAPT (0.39) GHSRALDH1A1KMT2AMAPTPPIA
SCHEMBL6519305 0.72 MAPT (0.40) GHSRALDH1A1KMT2AMAPT
SCHEMBL15114583 0.72 MAPT (0.40) GHSRALDH1A1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0862464-A4 AMINO ACID ANALOGS FOR TUMOR IMAGING UNIV EMORY (US) 2001-07-25 EP disclosed
US-5817776-A TECHNETIUM 99 COMPLEXES, SINGLE PHOTON EMISSION TOMOGRAPHY EMORY UNIVERSITY (US) 1998-10-06 US disclosed
US-5808146-A Amino acid analogs for tumor imaging EMORY UNIVERSITY (US) 1998-09-15 US disclosed
EP-0862464-A1 AMINO ACID ANALOGS FOR TUMOR IMAGING EMORY UNIVERSITY (US) 1998-09-09 EP disclosed
WO-1997017092-A1 AMINO ACID ANALOGS FOR TUMOR IMAGING EMORY UNIVERSITY (US) 1997-05-15 WO disclosed