Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 3/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938562 | 1.00 | HRH3 (0.37) | HRH3KDM1AHTTSIGMAR1CCR5 | |
| SCHEMBL7503238 | 1.00 | HRH3 (0.37) | HRH3KDM1AHTTSIGMAR1CCR5 | |
| SCHEMBL7544369 | 0.80 | CCR5 (0.48) | HRH3KDM1AHTTCCR5 | |
| SCHEMBL7492331 | 0.80 | CCR5 (0.48) | HRH3KDM1AHTTCCR5 | |
| SCHEMBL7940918 | 0.80 | CCR5 (0.48) | HRH3KDM1AHTTCCR5 | |
| SCHEMBL7497446 | 0.80 | HRH3 (0.44) | HRH3KDM1AHTTCCR5 | |
| SCHEMBL7986475 | 0.80 | HRH3 (0.44) | HRH3KDM1AHTTCCR5 | |
| SCHEMBL7986474 | 0.80 | HRH3 (0.44) | HRH3KDM1AHTTCCR5 | |
| SCHEMBL7491709 | 0.79 | HTT (0.37) | HRH3KDM1AHTTCCR5 | |
| SCHEMBL7502153 | 0.78 | CCR5 (0.40) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248755-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS; AUTOIMMUNE DISEASES | MERCK & CO., INC. | 2001-06-19 | — | — | US | disclosed |