Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992052 | 0.86 | ALDH1A1 (0.55) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL7985731 | 0.86 | MAPT (0.55) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL3129608 | 0.86 | MAPT (0.58) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL3122360 | 0.85 | ALDH1A1 (0.59) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL7947627 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL7948285 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL4566011 | 0.84 | ALDH1A1 (0.49) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL4307521 | 0.84 | ALDH1A1 (0.49) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL4305038 | 0.84 | MAPT (0.51) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL7949180 | 0.83 | ALDH1A1 (0.55) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035032-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |