Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929462 | 0.95 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL7846034 | 0.94 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL7937657 | 0.91 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL7929533 | 0.90 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL6814201 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL7929460 | 0.82 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL2995842 | 0.81 | HPGD (0.46) | ALDH1A1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL6697662 | 0.81 | KCNH2 (0.59) | MAPT | |
| SCHEMBL6709496 | 0.79 | NPSR1 (0.51) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL6709588 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4EHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248739-B1 | DNA POLYMERASE INHIBITORS EFFECTIVE AGAINST HERPESVIRUSES | PHARMACIA & UPJOHN COMPANY | 2001-06-19 | — | — | US | disclosed |