Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12405329 | 0.76 | KDM1A (0.41) | KDM1A | |
| SCHEMBL445306 | 0.76 | SIGMAR1 (0.41) | KDM1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7932506 | 0.75 | KDM1A (0.41) | KDM1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5190442 | 0.71 | GRIN1 (0.40) | KDM1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL383562 | 0.71 | GRIN2D (0.39) | KDM1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7882223 | 0.71 | GRIN2D (0.39) | KDM1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1645321 | 0.71 | GRIN2D (0.39) | KDM1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29724424 | 0.71 | GRIN2D (0.39) | KDM1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7353711 | 0.71 | GRIN2D (0.39) | KDM1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL19183215 | 0.71 | GRIN2D (0.39) | KDM1AGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300376-B1 | FOR THERAPY TO ACHIEVE SMOOTH MUSCLE RELAXING ACTIVITY AND/OR MAST CELL STABILIZING ACTIVITY AND/OR ANTI-INFLAMMATORY ACTIVITY | VENANTIUS LIMITED (IR) | 2001-10-09 | — | — | US | disclosed |