Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5211517 | 0.99 | KMT2A (0.48) | MEN1KMT2ATLR2TLR1KDM4C | |
| SCHEMBL24675724 | 0.86 | MEN1 (0.48) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL10007365 | 0.86 | MEN1 (0.49) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL22071027 | 0.85 | KMT2A (0.49) | MEN1KMT2AKDM4CCES2POLB | |
| SCHEMBL21068614 | 0.83 | KMT2A (0.47) | MEN1KMT2AKDM4CCES2 | |
| SCHEMBL8014306 | 0.82 | MEN1 (0.58) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL5218740 | 0.81 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL5218731 | 0.81 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL18294545 | 0.81 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL23930447 | 0.80 | MEN1 (0.43) | MEN1KMT2AKDM4CNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245317-B1 | F18-labeled oxa fatty acids and methods of making and using the same | DUKE UNIVERSITY | 2001-06-12 | — | — | US | disclosed |