SCHEMBL7939109

SCHEMBL7939109

COCOc1ccc(I)c(F)c1F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 1/20 0.31
KCNN4 O15554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29742117 0.82 L3MBTL1 (0.40)
SCHEMBL17527871 0.82 L3MBTL1 (0.40)
SCHEMBL2821417 0.82 L3MBTL1 (0.40)
SCHEMBL31566435 0.80 FFAR1 (0.37) MRGPRX4KCNN4
SCHEMBL422284 0.80 EPAS1 (0.36)
SCHEMBL17528451 0.78 PTPN1 (0.36) MRGPRX4KCNN4
SCHEMBL17993346 0.77 TUBB1 (0.37) MRGPRX4
SCHEMBL8831943 0.77 MRGPRX4 (0.31) MRGPRX4KCNN4
SCHEMBL28427120 0.76 CYP1A2 (0.42)
SCHEMBL31166945 0.75 PTPN1 (0.42) MRGPRX4KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6329027-B1 Chlorobenzene derivatives, liquid-crystal composition, and liquid-crystal display elements CHISSO CORPORATION (JP) 2001-12-11 US disclosed
EP-0959060-A1 CHLOROBENZENE DERIVATIVES, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENTS CHISSO CORPORATION (JP) 1999-11-24 EP disclosed