Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003197 | 0.88 | MAPK1 (0.56) | MAPK1KDM4EL3MBTL1ALDH1A1HPGD | |
| SCHEMBL1000357 | 0.83 | MAPK1 (0.54) | MAPK1KDM4EL3MBTL1ALDH1A1HPGD | |
| SCHEMBL7940985 | 0.80 | MAPK1 (0.68) | MAPK1KDM4EL3MBTL1NPC1RAB9A | |
| SCHEMBL7882276 | 0.72 | MAPK1 (0.74) | MAPK1KDM4EL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL1004608 | 0.72 | MAPK1 (0.64) | MAPK1KDM4EL3MBTL1HPGDNPC1 | |
| SCHEMBL69747 | 0.72 | MAPK1 (1.00) | MAPK1KDM4EL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL29508473 | 0.72 | MAPK1 (1.00) | MAPK1KDM4EL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL26984690 | 0.72 | MAPK1 (0.68) | MAPK1KDM4EL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL29153940 | 0.71 | MAPK1 (0.66) | MAPK1KDM4EL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL7356681 | 0.70 | MAPK1 (0.75) | MAPK1KDM4EL3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017079-A1 | OXAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH | MERCK & CO., INC. (US) | 2010-02-11 | — | — | WO | disclosed |