Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 10/20 | 0.51 |
| ▸ | IDO1 | P14902 | 4/20 | 0.47 |
| ▸ | TDO2 | P48775 | 2/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1492761 | 1.00 | TACR1 (0.51) | TACR1IDO1TDO2PDE2ACACNA1F | |
| SCHEMBL6917133 | 1.00 | TACR1 (0.51) | TACR1IDO1TDO2PDE2ACACNA1F | |
| SCHEMBL336049 | 1.00 | TACR1 (0.51) | TACR1IDO1TDO2PDE2ACACNA1F | |
| SCHEMBL1728680 | 1.00 | TACR1 (0.51) | TACR1IDO1TDO2PDE2ACACNA1F | |
| Hydrochloric Acid SCHEMBL4471353 | 0.98 | TACR1 (0.50) | TACR1IDO1TDO2PDE2ACACNA1F | |
| Methane SCHEMBL4258949 | 0.98 | TACR1 (0.50) | TACR1IDO1TDO2PDE2ACACNA1F | |
| Hydrochloric Acid SCHEMBL7170075 | 0.98 | TACR1 (0.50) | TACR1IDO1TDO2PDE2ACACNA1F | |
| Hydrochloric Acid SCHEMBL17439064 | 0.98 | TACR1 (0.50) | TACR1IDO1TDO2PDE2ACACNA1F | |
| SCHEMBL29799650 | 0.88 | TACR1 (0.44) | TACR1IDO1TDO2PDE2ACACNA1F | |
| SCHEMBL29799603 | 0.88 | TACR1 (0.44) | TACR1IDO1TDO2PDE2ACACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |