Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | CETP | P11597 | 2/20 | 0.32 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL654618 | 0.82 | PI4KB (0.56) | PI4KBALDH1A1 | |
| SCHEMBL652728 | 0.74 | PI4KB (0.57) | PI4KBALDH1A1 | |
| SCHEMBL1694444 | 0.74 | PI4KB (0.52) | PI4KBALDH1A1NPSR1 | |
| SCHEMBL655377 | 0.71 | PI4KB (0.59) | PI4KB | |
| SCHEMBL657140 | 0.68 | PI4KB (0.58) | PI4KBALDH1A1 | |
| SCHEMBL16428361 | 0.68 | LMNA (0.46) | HRH4PI4KBALDH1A1 | |
| SCHEMBL653896 | 0.66 | PI4KB (0.62) | PI4KB | |
| SCHEMBL1694165 | 0.65 | GPR183 (0.52) | PI4KBALDH1A1 | |
| SCHEMBL653158 | 0.63 | PI4KB (0.58) | PI4KB | |
| SCHEMBL654736 | 0.61 | PI4KB (0.62) | PI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616077-A1 | ANTI-CANCER ACTIVITY OF NOVEL BICYCLIC HETEROCYCLES | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2013-07-24 | — | — | EP | claimed |
| WO-2012035423-A1 | ANTI-CANCER ACTIVITY OF NOVEL BICYCLIC HETEROCYCLES | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) | 2012-03-22 | — | — | WO | claimed |