Biphenyl

Biphenyl

SCHEMBL7939259

C#COC#C.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
AKT1 P31749 1/20 0.42
AKT2 P31751 1/20 0.42
CYP1A2 P05177 2/20 0.39
MAPK1 P28482 2/20 0.39
TAAR1 Q96RJ0 2/20 0.39
CYP3A4 P08684 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NOTUM Q6P988 1/20 0.39
MMP3 P08254 1/20 0.39
BCL2L1 Q07817 1/20 0.39
CYP1A1 P04798 1/20 0.37
CYP1B1 Q16678 1/20 0.37
RAB9A P51151 2/20 0.36
PYCR1 P32322 1/20 0.36
MAPT P10636 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ATM Q13315 1/20 0.36
SLC22A2 O15244 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL8358517 0.78 ALDH1A1 (0.64) ALDH1A1CYP1A2MAPK1TAAR1CYP3A4
Biphenyl SCHEMBL27412181 0.75 ALDH1A1 (0.60) ALDH1A1CYP1A2MAPK1TAAR1CYP3A4
Biphenyl SCHEMBL27831016 0.75 ALDH1A1 (0.60) ALDH1A1CYP1A2MAPK1TAAR1CYP3A4
Biphenyl SCHEMBL28416844 0.75 ALDH1A1 (0.60) ALDH1A1CYP1A2MAPK1TAAR1CYP3A4
Biphenyl SCHEMBL351372 0.73 ALDH1A1 (0.82) ALDH1A1CYP1A2MAPK1TAAR1CYP3A4
Biphenyl SCHEMBL27713088 0.73 ALDH1A1 (0.82) ALDH1A1CYP1A2MAPK1TAAR1CYP3A4
Biphenyl SCHEMBL8769842 0.73 ALDH1A1 (0.82) ALDH1A1CYP1A2MAPK1TAAR1CYP3A4
Biphenyl SCHEMBL164 0.73 ALDH1A1 (1.00) ALDH1A1CYP1A2MAPK1TAAR1CYP3A4
Biphenyl SCHEMBL28890607 0.73 ALDH1A1 (1.00) ALDH1A1CYP1A2MAPK1TAAR1CYP3A4
Biphenyl SCHEMBL1358618 0.73 ALDH1A1 (1.00) ALDH1A1CYP1A2MAPK1TAAR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7211142-A None JP disclosed
EP-0834499-B1 Process for the preparation of aromatic vinyl compounds DAINIPPON INK & CHEMICALS (JP) 2001-07-25 EP disclosed
EP-0834499-A1 Process for the preparation of aromatic vinyl compounds DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-04-08 EP disclosed
JP-H07211142-A DIELECTRIC LAYER DEFINABLE WITH LIGHT INCLUDING POLY (AROMATIC DIACETYLENE) AT & T CORP 1995-08-11 JP disclosed