SCHEMBL7939281

SCHEMBL7939281

CCCCC=C(C)C(=O)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.39
GRIK1 P39086 1/20 0.36
TSHR P16473 2/20 0.36
F7 P08709 1/20 0.34
F3 P13726 1/20 0.34
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
GMNN O75496 1/20 0.33
USP2 O75604 1/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CES1 P23141 1/20 0.32
FAAH O00519 1/20 0.32
CES2 O00748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7939276 1.00 EP300 (0.39) EP300GRIK1TSHRF7F3
SCHEMBL9799758 0.79 EP300 (0.36) EP300GRIK1TSHRF7F3
SCHEMBL9799762 0.79 EP300 (0.36) EP300GRIK1TSHRF7F3
SCHEMBL1785114 0.78 EP300 (0.45) EP300GRIK1TSHRF7F3
SCHEMBL309931 0.78 EP300 (0.45) EP300GRIK1TSHRF7F3
SCHEMBL18349201 0.78 ALDH1A1 (0.30) ALDH1A1
SCHEMBL27885956 0.76 EP300 (0.34) EP300GRIK1TSHRF7F3
SCHEMBL6910247 0.76 EP300 (0.54) EP300GRIK1TSHRF7F3
SCHEMBL2406221 0.76 EP300 (0.54) EP300GRIK1TSHRF7F3
SCHEMBL22546 0.76 EP300 (0.54) EP300GRIK1TSHRF7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0768294-B1 Process for preparing 2,4,4,7-tetramethyl-oct-6-en-3-on and its use as perfume HAARMANN & REIMER GMBH (DE) 2001-09-12 EP disclosed
US-6252120-B1 ALKENYLATION OF DIISOPROPYL KETONE WITH 1-CHLORO-3-METHYL-2-BUTENE IN AN AQUEOUS PHASE CATALYZED BY A PHASE TRANSFER CATALYST HAARMANN & REIMER GMBH (DE) 2001-06-26 US disclosed
EP-0768294-A1 Process for preparing 2,4,4,7-tetramethyl-oct-6-en-3-on and its use as perfume HAARMANN & REIMER GMBH (DE) 1997-04-16 EP disclosed