Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14484876 | 0.74 | THRB (0.40) | THRBLMNA | |
| SCHEMBL442787 | 0.74 | THRB (0.40) | THRBLMNA | |
| SCHEMBL1400060 | 0.70 | THRB (0.36) | THRBLMNA | |
| SCHEMBL22534494 | 0.70 | THRB (0.36) | THRBLMNA | |
| SCHEMBL1400047 | 0.70 | THRB (0.36) | THRBLMNA | |
| SCHEMBL1561850 | 0.70 | THRB (0.43) | THRBLMNA | |
| SCHEMBL10840016 | 0.68 | THRB (0.44) | THRBLMNA | |
| SCHEMBL23740332 | 0.67 | — | — | |
| SCHEMBL441768 | 0.67 | THRB (0.38) | THRBLMNA | |
| SCHEMBL25688960 | 0.67 | THRB (0.38) | THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046869-A2 | TETRAHYDRONAPHTHALENE COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046729-A2 | TETRAHYDRONAPHTHALENE COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-29 | — | — | WO | disclosed |