SCHEMBL7939345

SCHEMBL7939345

CCCCN(Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1)c1ncncc1C(=O)O

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 16/20 0.72
AGTR2 P50052 16/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9589182 0.99 AGTR1 (0.74) AGTR1AGTR2
Hydrochloric Acid SCHEMBL9589709 0.94 AGTR1 (0.72) AGTR1AGTR2
SCHEMBL9590097 0.90 AGTR1 (0.60) AGTR1AGTR2
SCHEMBL9589609 0.88 AGTR1 (0.73) AGTR1AGTR2
SCHEMBL9590480 0.88 AGTR1 (0.59) AGTR1AGTR2
SCHEMBL9591236 0.87 AGTR1 (0.58) AGTR1AGTR2
SCHEMBL9591954 0.87 AGTR1 (0.58) AGTR1AGTR2
SCHEMBL9599497 0.87 AGTR1 (0.74) AGTR1AGTR2
Hydrochloric Acid SCHEMBL9591762 0.87 AGTR1 (0.74) AGTR1AGTR2
Methylamine SCHEMBL9590818 0.86 AGTR1 (0.71) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0475206-A2 Angiotensin II receptor antagonists ABBOTT LABORATORIES (US) 1992-03-18 EP claimed
US-6218414-B1 ADMINISTERING AN EFFECTIVE AMOUNT OF AN ANGIOTENSIN II ANTAGONIST AND A BENZOFURAN DERIVATIVE WITH ANTIARRHYTHMIC ACTIVITY FOR THERAPY OF CARDIOVASCULAR COMPLAINTS SANOFI (FR) 2001-04-17 US disclosed
US-5250548-A Treating hypertension, heart failure ABBOTT LABORATORIES (US) 1993-10-05 US disclosed
EP-0475206-A2 Angiotensin II receptor antagonists ABBOTT LABORATORIES (US) 1992-03-18 EP disclosed