Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.42 |
| ▸ | HTR2C | P28335 | 6/20 | 0.42 |
| ▸ | HTR2B | P41595 | 6/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19756651 | 0.86 | MAPT (0.41) | HTR2AHTR2CHTR2BTUBB1MAPT | |
| SCHEMBL12804213 | 0.84 | HTR2A (0.47) | HTR2AHTR2CHTR2BTUBB1MAPT | |
| SCHEMBL19756656 | 0.82 | HTR2A (0.46) | HTR2AHTR2CHTR2BTUBB1PTGS2 | |
| SCHEMBL15334770 | 0.80 | HTR2A (0.41) | HTR2AHTR2CHTR2BTUBB1PTGS2 | |
| SCHEMBL12180281 | 0.79 | TUBB1 (0.43) | HTR2AHTR2CHTR2BTUBB1PTGS2 | |
| SCHEMBL30426101 | 0.79 | TUBB1 (0.43) | HTR2AHTR2CHTR2BTUBB1PTGS2 | |
| SCHEMBL23723833 | 0.78 | KMT2A (0.42) | HTR2AHTR2CHTR2BTUBB1MAPT | |
| SCHEMBL4406929 | 0.78 | HTR2A (0.44) | HTR2AHTR2CHTR2BMAPTRAB9A | |
| SCHEMBL7723707 | 0.78 | HTR2A (0.41) | HTR2AHTR2CHTR2BTUBB1MAPT | |
| SCHEMBL2883982 | 0.78 | NQO2 (0.38) | HTR2AHTR2CHTR2BTUBB1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1138657-A1 | Process for generating electrophiles from anions by reaction with electrophilic fluorinating agent | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2001-10-04 | — | — | EP | disclosed |
| US-6270843-B1 | REACTING A SALT COMPRISING ANIONIC FORM OF SUBSTITUENT WITH AN ELECTROPHILIC FLUORINATION AGENT TO PROVIDE AN ELECTROPHILE COMPRISING CATIONIC FORM OF SUBSTITUENT; ELECTROPHILICALLY SUBSTITUTING ELECTROPHILE ON SUBSTRATE | AIR PRODUCTS AND CHEMICALS, INC. | 2001-08-07 | — | — | US | disclosed |