Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | HTR2B | P41595 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12804213 | 0.80 | HTR2A (0.47) | HTR2AHTR2CHTR2BMAPTRAB9A | |
| SCHEMBL7939401 | 0.78 | HTR2A (0.42) | HTR2AHTR2CHTR2BMAPTRAB9A | |
| SCHEMBL30315940 | 0.78 | TUBB1 (0.40) | HTR2AHTR2CHTR2BRAB9AHTT | |
| SCHEMBL30630190 | 0.78 | TUBB1 (0.40) | HTR2AHTR2CHTR2BRAB9AHTT | |
| SCHEMBL24321596 | 0.77 | CA2 (0.40) | MAPTRAB9AHTTMAPK1LMNA | |
| SCHEMBL15334770 | 0.77 | HTR2A (0.41) | HTR2AHTR2CHTR2BMAPTRAB9A | |
| SCHEMBL30330075 | 0.77 | CA2 (0.40) | MAPTRAB9AHTTMAPK1LMNA | |
| SCHEMBL31466896 | 0.77 | MAPT (0.38) | HTR2AHTR2CHTR2BMAPTRAB9A | |
| SCHEMBL4406929 | 0.75 | HTR2A (0.44) | HTR2AHTR2CHTR2BMAPTRAB9A | |
| SCHEMBL21624297 | 0.75 | MAPT (0.48) | HTR2AHTR2CHTR2BMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1127457-C | Process for electrophilic aromatic substitution | BROMINE COMPOUNDS LTD (IL) | 2003-11-12 | — | — | CN | disclosed |
| US-6399835-B1 | ALKYLATION, HALOGENATION USING AQUEOUS SOLUTION OF ZINC HALIDE | BROMINE COMPOUNDS LTD. (IL) | 2002-06-04 | — | — | US | disclosed |
| CN-1280555-A | Process for electrophilic aromatic substitution | BROMINE COMPOUNDS LTD (IL) | 2001-01-17 | — | — | CN | disclosed |
| EP-1032549-A1 | PROCESS FOR ELECTROPHILIC AROMATIC SUBSTITUTION | Bromine Compounds Ltd. (IL) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999019275-A1 | PROCESS FOR ELECTROPHILIC AROMATIC SUBSTITUTION | BROMINE COMPOUNDS LTD. (IL) | 1999-04-22 | — | — | WO | disclosed |