Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597055 | 0.95 | CNR1 (0.38) | LMNAPPARGPPARDPPARACNR1 | |
| SCHEMBL3432184 | 0.95 | CNR1 (0.38) | LMNAPPARGPPARDPPARACNR1 | |
| SCHEMBL818112 | 0.95 | — | — | |
| SCHEMBL818113 | 0.95 | — | — | |
| SCHEMBL817714 | 0.87 | LMNA (0.43) | LMNAPPARGPPARDPPARACNR1 | |
| SCHEMBL817715 | 0.87 | LMNA (0.43) | LMNAPPARGPPARDPPARACNR1 | |
| SCHEMBL2008818 | 0.85 | LMNA (0.42) | LMNAPPARGCNR1HIF1AEPAS1 | |
| SCHEMBL2007796 | 0.85 | LMNA (0.42) | LMNAPPARGCNR1HIF1AEPAS1 | |
| SCHEMBL2007794 | 0.85 | LMNA (0.42) | LMNAPPARGCNR1HIF1AEPAS1 | |
| SCHEMBL2008820 | 0.85 | LMNA (0.42) | LMNAPPARGCNR1HIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616056-A1 | TERPENOID ANALOGUES AND USES THEREOF FOR TREATING NEUROLOGICAL CONDITIONS | Neuroquest Inc. (CA) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012034232-A1 | TERPENOID ANALOGUES AND USES THEREOF FOR TREATING NEUROLOGICAL CONDITIONS | NEUROQUEST INC. (CA) | 2012-03-22 | — | — | WO | disclosed |