Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 15/20 | 0.40 |
| ▸ | NMBR | P28336 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1097103 | 0.94 | SIRT2 (0.42) | SIRT2NMBRCYP11B1CYP11B2ENPP2 | |
| SCHEMBL8543176 | 0.89 | SIRT2 (0.40) | SIRT2NMBRCYP11B1CYP11B2ENPP2 | |
| SCHEMBL1342 | 0.84 | SIRT2 (0.45) | SIRT2NMBRCYP11B1CYP11B2ENPP2 | |
| SCHEMBL6771514 | 0.83 | SIRT2 (0.44) | SIRT2NMBRCYP11B1CYP11B2ENPP2 | |
| SCHEMBL1037597 | 0.82 | SIRT2 (0.45) | SIRT2NMBRCYP11B1CYP11B2ENPP2 | |
| SCHEMBL7713289 | 0.81 | SIRT2 (0.46) | SIRT2NMBR | |
| SCHEMBL1039638 | 0.81 | SIRT2 (0.43) | SIRT2NMBRCYP11B1CYP11B2 | |
| Acetic Acid SCHEMBL7659782 | 0.80 | SIRT2 (0.47) | SIRT2NMBRCYP11B1CYP11B2ENPP2 | |
| SCHEMBL1039740 | 0.80 | SIRT2 (0.43) | SIRT2NMBRCYP11B1CYP11B2 | |
| SCHEMBL9069663 | 0.79 | SIRT2 (0.44) | SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017992-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |