Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13003243 | 0.74 | KDM4E (0.42) | KDM4EALDH1A1RAB9AHPGDMAPT | |
| SCHEMBL11932351 | 0.74 | KDM4E (0.42) | KDM4EALDH1A1RAB9AHPGDMAPT | |
| SCHEMBL13845397 | 0.74 | KDM4E (0.42) | KDM4EALDH1A1RAB9AHPGDMAPT | |
| SCHEMBL14538678 | 0.70 | ABL1 (0.37) | ABL1 | |
| SCHEMBL16504220 | 0.65 | HDAC1 (0.35) | HDAC1HDAC8HDAC6 | |
| SCHEMBL24221414 | 0.65 | KDM4E (0.39) | KDM4EGAAALDH1A1RAB9AHPGD | |
| Dipyridyl SCHEMBL4881410 | 0.64 | KDM4E (0.67) | KDM4EALDH1A1RAB9AHPGDMAPT | |
| Dipyridyl SCHEMBL11231947 | 0.64 | KDM4E (0.67) | KDM4EALDH1A1RAB9AHPGDMAPT | |
| Dipyridyl SCHEMBL9641711 | 0.64 | KDM4E (0.67) | KDM4EALDH1A1RAB9AHPGDMAPT | |
| Dipyridyl SCHEMBL30976994 | 0.63 | KDM4E (0.74) | KDM4EALDH1A1RAB9AHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025235-A1 | SELECTIVE LIGANDS FOR THE DOPAMINE 3 (D3) RECEPTOR AND METHODS OF USING THE SAME | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-03-04 | — | — | WO | disclosed |