Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.75 |
| ▸ | EDNRA | P25101 | 11/20 | 0.65 |
| ▸ | CCR4 | P51679 | 8/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL795587 | 0.89 | ABCB11 (0.78) | ABCB11EDNRACCR4 | |
| SCHEMBL7358242 | 0.89 | ABCB11 (0.81) | ABCB11EDNRACCR4 | |
| SCHEMBL7357895 | 0.88 | ABCB11 (0.79) | ABCB11EDNRACCR4 | |
| SCHEMBL7363876 | 0.87 | ABCB11 (0.75) | ABCB11EDNRACCR4 | |
| SCHEMBL7365895 | 0.87 | ABCB11 (0.78) | ABCB11EDNRACCR4 | |
| SCHEMBL7362617 | 0.86 | ABCB11 (0.77) | ABCB11EDNRACCR4 | |
| SCHEMBL7366024 | 0.86 | ABCB11 (1.00) | ABCB11EDNRACCR4 | |
| SCHEMBL7365241 | 0.85 | ABCB11 (0.75) | ABCB11EDNRACCR4 | |
| SCHEMBL7359279 | 0.85 | ABCB11 (0.75) | ABCB11EDNRACCR4 | |
| SCHEMBL30296218 | 0.85 | ABCB11 (0.75) | ABCB11EDNRACCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001049289-A1 | PHARMACEUTICAL AND VETERINARY USES OF ENDOTHELIN ANTAGONISTS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2001-07-12 | — | — | WO | disclosed |