SCHEMBL7939722

SCHEMBL7939722

O=CCCC(=O)C(=O)C(=O)CCC=O

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.37
HPGD P15428 1/20 0.34
ALDH1A1 P00352 1/20 0.33
EGLN1 Q9GZT9 2/20 0.32
LMNA P02545 1/20 0.32
ALKBH5 Q6P6C2 1/20 0.32
SUCNR1 Q9BXA5 1/20 0.32
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
SLC13A3 Q8WWT9 1/20 0.30
OR51E2 Q9H255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL665744 0.79 OR51E2 (0.55) HIF1AHPGDALDH1A1EGLN1LMNA
SCHEMBL60431 0.79
SCHEMBL5032513 0.77 HIF1A (0.33) HIF1AHPGDALDH1A1
SCHEMBL28327681 0.77
SCHEMBL7941814 0.77
SCHEMBL30213710 0.77 HIF1A (0.47) HIF1AHPGDALDH1A1TSHR
SCHEMBL712491 0.75
SCHEMBL7930251 0.75 HIF1A (0.32) HIF1AHPGDTSHR
SCHEMBL11851536 0.75 HIF1A (0.32) HIF1AHPGD
SCHEMBL9618343 0.73 HIF1A (0.41) HIF1AHPGDALDH1A1EGLN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6250317-B1 DISSOLVING THE FILM OF A CROSSLINKED RESIN OF A CARBONYL GROUP CONTAINING COMPOUND AND HYDRAZIDE COMPOUND IN A MIXTURE OF ACIDS (ORGANIC AND INORGANIC), WATER, AND SOLVENTS KANSAI PAINT CO. LTD (JP) 2001-06-26 US disclosed