Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.55 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.37 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60431 | 1.00 | — | — | |
| Alpha-Ketoglutaric Acid SCHEMBL12760653 | 0.87 | EGLN1 (0.70) | OR51E2EGLN1MAPK1SLC13A3LMNA | |
| SCHEMBL1296671 | 0.83 | OR51E2 (0.50) | OR51E2EGLN1MAPK1SLC13A3LMNA | |
| SCHEMBL14386822 | 0.81 | MAPK1 (0.48) | OR51E2EGLN1MAPK1SLC13A3LMNA | |
| SCHEMBL23174677 | 0.79 | MAPK1 (0.46) | OR51E2EGLN1MAPK1SLC13A3LMNA | |
| SCHEMBL28777797 | 0.79 | MAPK1 (0.46) | OR51E2EGLN1MAPK1SLC13A3LMNA | |
| SCHEMBL21600769 | 0.79 | MAPK1 (0.46) | OR51E2EGLN1MAPK1SLC13A3LMNA | |
| SCHEMBL11678127 | 0.79 | MAPK1 (0.46) | OR51E2EGLN1MAPK1SLC13A3LMNA | |
| Benzene SCHEMBL8775366 | 0.79 | OR51E2 (0.46) | OR51E2EGLN1MAPK1SLC13A3LMNA | |
| SCHEMBL7939722 | 0.79 | HIF1A (0.37) | OR51E2EGLN1MAPK1SLC13A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102762735-B | Microorganisms producing 1, 4-butanediol, 4-hydroxybutyraldehyde, 4-hydroxybutyryl-COA, putrescine and related compounds and related methods | 基因组股份公司 | 2016-08-03 | — | — | CN | disclosed |
| US-20120045804-A1 | CONVERSION OF HEXURONIC ACID TO HEXARIC ACID | TEKNOLOGIAN TUTKIMUSKESKUS VTT (FI) | 2012-02-23 | — | — | US | disclosed |
| EP-2376620-A1 | CONVERSION OF HEXURONIC ACID TO HEXARIC ACID | Teknologian Tutkimuskeskus VTT (FI) | 2011-10-19 | — | — | EP | disclosed |