Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30877065 | 0.92 | TSHR (0.33) | TSHRALDH1A1MEN1LMNACYP3A4 | |
| SCHEMBL30877066 | 0.89 | TSHR (0.32) | TSHR | |
| SCHEMBL30877068 | 0.88 | TSHR (0.35) | TSHRALDH1A1MEN1LMNACYP3A4 | |
| SCHEMBL30877067 | 0.86 | TSHR (0.34) | TSHRALDH1A1MEN1LMNACYP3A4 | |
| SCHEMBL7950633 | 0.85 | TSHR (0.38) | TSHRALDH1A1MEN1LMNACYP3A4 | |
| SCHEMBL7059830 | 0.81 | TSHR (0.35) | TSHRALDH1A1MEN1LMNACYP3A4 | |
| SCHEMBL30018016 | 0.80 | TSHR (0.46) | TSHRALDH1A1MEN1LMNACYP3A4 | |
| SCHEMBL8040190 | 0.77 | TSHR (0.41) | TSHRALDH1A1MEN1LMNACYP3A4 | |
| SCHEMBL7125831 | 0.76 | TSHR (0.37) | TSHRALDH1A1MEN1LMNACYP3A4 | |
| SCHEMBL9752447 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248840-B1 | ETHYLENE POLYMER; BLOW MOLDING, CLARITY, HIGH STRENGTH | PHILLIPS PETROLEUM COMPANY | 2001-06-19 | — | — | US | disclosed |
| US-5962592-A | CROSSLINKING; USING A METALLOCENE CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1999-10-05 | — | — | US | disclosed |
| EP-0870803-A1 | A process to produce a crosslinked composition that comprises polymers that comprise ethylene and a crosslinked composition that comprises polymers that comprise ethylene | PHILLIPS PETROLEUM COMPANY (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5405915-A | Ethylene polymer; crosslinking agent; nonaromatic, cyclic, unsaturated crosslinking co-agent; consistent tensile properties | PHILLIPS PETROLEUM COMPANY (US) | 1995-04-11 | — | — | US | disclosed |