Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29182907 | 0.88 | CA2 (0.46) | NOTUMCA2CA4HSD17B10SMN1; SMN2 | |
| SCHEMBL1188715 | 0.86 | CA2 (0.36) | NOTUMCA2CA4HSD17B10SMN1; SMN2 | |
| SCHEMBL13807389 | 0.82 | HSD17B10 (0.46) | NOTUMCA2CA4HSD17B10SMN1; SMN2 | |
| SCHEMBL1119270 | 0.82 | CA2 (0.42) | NOTUMCA2CA4HSD17B10SMN1; SMN2 | |
| SCHEMBL31063094 | 0.81 | CA2 (0.41) | NOTUMCA2CA4HSD17B10SMN1; SMN2 | |
| SCHEMBL24252358 | 0.79 | CA2 (0.39) | NOTUMCA2CA4HSD17B10SMN1; SMN2 | |
| SCHEMBL896507 | 0.79 | CA2 (0.44) | NOTUMCA2CA4HSD17B10SMN1; SMN2 | |
| SCHEMBL7878366 | 0.77 | CACNA1H (0.36) | NOTUMCACNA1HSMN1; SMN2CRHR1TPMT | |
| SCHEMBL3770921 | 0.74 | CA2 (0.42) | CA2CA4HSD17B10PTGS2LMNA | |
| SCHEMBL13807390 | 0.74 | NOTUM (0.49) | NOTUMHSD17B10SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268527-B1 | REACTING TRIFLUOROMETHYL SUBSTITUTED AROMATIC COMPOUND WITH CARBON MONOXIDE AND HYDROXY COMPOUND IN PRESENCE OF METAL COMPOUND AND PHOSPHINE DERIVATIVE TO PRODUCE TRIFLUOROMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVE | CENTRAL GLASS COMPANY, LIMITED (JP) | 2001-07-31 | — | — | US | disclosed |