Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | ELANE | P08246 | 4/20 | 0.55 |
| ▸ | PLG | P00747 | 4/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29410971 | 0.95 | ADORA3 (0.61) | PPARGPLGADORA3L3MBTL1ACE2 | |
| SCHEMBL118391 | 0.95 | ADORA3 (0.61) | PPARGPLGADORA3L3MBTL1ACE2 | |
| Benzquercin SCHEMBL1057326 | 0.91 | PPARG (0.66) | PPARGELANEPLGADORA3L3MBTL1 | |
| SCHEMBL30424171 | 0.91 | PPARG (0.69) | PPARGELANEPLGADORA3L3MBTL1 | |
| SCHEMBL1421560 | 0.89 | ACE2 (0.69) | PPARGELANEPLGADORA3L3MBTL1 | |
| SCHEMBL16151312 | 0.88 | PPARG (0.71) | PPARGELANEPLGADORA3L3MBTL1 | |
| SCHEMBL31031155 | 0.88 | PPARG (0.78) | PPARGELANEPLGADORA3L3MBTL1 | |
| SCHEMBL31031143 | 0.88 | PPARG (0.62) | PPARGELANEPLGADORA3L3MBTL1 | |
| SCHEMBL28516722 | 0.87 | PPARG (0.53) | PPARGELANEPLGADORA3ACE2 | |
| SCHEMBL31031148 | 0.86 | ADORA3 (0.58) | PPARGPLGADORA3L3MBTL1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258840-B1 | ANTITUMOR AGENTS, ANTIINFLAMMATORY AGENTS, ENZYME INHIBITORS OF KINASES | COBRA THERAPEUTICS LIMITED (GB) | 2001-07-10 | — | — | US | disclosed |
| EP-0912541-A1 | ANALOGUES OR DERIVATIVES OF QUERCETIN (PRODRUGS) | Cobra Therapeutics Limited (GB) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997049693-A1 | ANALOGUES OR DERIVATIVES OF QUERCETIN (PRODRUGS) | COBRA THERAPEUTICS LIMITED (GB) | 1997-12-31 | — | — | WO | disclosed |