Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB1 | P11230 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1605849 | 0.84 | KMT2A (0.49) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL1605850 | 0.84 | KMT2A (0.49) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL1605519 | 0.79 | KMT2A (0.54) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL1605789 | 0.75 | CHRNB1 (0.58) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL1606261 | 0.75 | CHRNB1 (0.51) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL1605878 | 0.72 | KMT2A (0.55) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL16196639 | 0.72 | KMT2A (0.58) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL1605168 | 0.72 | KMT2A (0.58) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL1605248 | 0.72 | KMT2A (0.58) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL1605979 | 0.72 | KMT2A (0.58) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009156462-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-12-30 | — | — | WO | disclosed |