Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MGAM | O43451 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SI | P14410 | 2/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL27608229 | 0.88 | MGAM (0.68) | LMNAMGAMGAASIMGAM2 | |
| Dimethyl Succinate SCHEMBL27918747 | 0.87 | TSHR (0.65) | LMNAMGAMGAASIMGAM2 | |
| Acrylic Acid SCHEMBL27723623 | 0.85 | LMNA (0.48) | LMNAMGAMGAASIMGAM2 | |
| Acrylic Acid SCHEMBL27604186 | 0.83 | LMNA (0.46) | LMNAMGAMGAASIMGAM2 | |
| Acrylic Acid SCHEMBL11238765 | 0.83 | HSD17B10 (0.45) | LMNAMGAMGAASIMGAM2 | |
| SCHEMBL27632379 | 0.81 | MGAM (0.50) | LMNAMGAMGAASIMGAM2 | |
| Acrylic Acid SCHEMBL235880 | 0.80 | — | — | |
| Acrylic Acid SCHEMBL11402222 | 0.80 | LMNA (0.71) | LMNATSHRHSD17B10ALOX15ALDH1A1 | |
| Ethylene SCHEMBL29245647 | 0.80 | MGAM (0.61) | LMNAMGAMGAASIMGAM2 | |
| SCHEMBL3441102 | 0.80 | MGAM (0.69) | LMNAMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618956-B1 | POLYFUNCTIONAL MICHAEL ADDITION PRODUCTS AND REFRIGERATION COMPOSITIONS CONTAINING SUCH PRODUCTS | ALBEMARLE CORP (US) | 2001-07-11 | — | — | EP | disclosed |
| US-5683618-A | MIXTURES OF ESTERS, KETONES OR NITRILES FOR LUBRICANTS FOR STABILITY | ALBEMARLE CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| US-5569779-A | ESTER OILS; LUBRICANTS | ALBEMARLE CORPORATION (US) | 1996-10-29 | — | — | US | disclosed |
| US-5430177-A | Polyfunctional Michael addition products | ALBEMARLE CORPORATION (US) | 1995-07-04 | — | — | US | disclosed |
| US-5391312-A | Seal-swell ester oils to counteract seal shrinkage | ALBEMARLE CORPORTION (US) | 1995-02-21 | — | — | US | disclosed |