Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | TPH1 | P17752 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.49 |
| ▸ | PDE4A | P27815 | 9/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937862 | 0.81 | RECQL (0.52) | RECQLTPH1PDE4BPDE4APDE4C | |
| SCHEMBL7422660 | 0.81 | PDE4B (0.49) | RECQLTPH1PDE4BPDE4APDE4C | |
| SCHEMBL309631 | 0.80 | TPH1 (0.51) | RECQLTPH1PDE4BPDE4APDE4C | |
| SCHEMBL1713655 | 0.80 | TPH1 (0.51) | RECQLTPH1PDE4BPDE4APDE4C | |
| SCHEMBL307931 | 0.80 | TPH1 (0.49) | RECQLTPH1PDE4BPDE4APDE4C | |
| SCHEMBL13317191 | 0.79 | RECQL (0.61) | RECQLPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7471407 | 0.79 | PDE4B (0.50) | RECQLTPH1PDE4BPDE4APDE4C | |
| SCHEMBL27589238 | 0.79 | RECQL (0.50) | RECQLTPH1PDE4BPDE4APDE4C | |
| SCHEMBL308215 | 0.79 | TPH1 (0.49) | RECQLTPH1PDE4BPDE4APDE4C | |
| SCHEMBL7424560 | 0.78 | RECQL (0.49) | RECQLTPH1PDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101257904-A | Pharmaceutical composition of a pde4 or a pde3/4 inhibitor and a histamine receptor antagonist | NYCOMED GMBH (DE) | 2008-09-03 | — | — | CN | claimed |
| US-5922751-A | BRONCHODILATOR AND ANTIINFLAMMATORY AGENT WITHOUT UNDESIRABLE CARDIOVASCULAR STIMULATION CAUSED BY PHOSPHODIESTERASE III INHIBITOR | EURO-CELTIQUE, S.A. (LU) | 1999-07-13 | — | — | US | claimed |
| US-6248769-B1 | ANTIINFLAMMATORY AGENT | EURO-CELTIQUE S.A. (LU) | 2001-06-19 | — | — | US | disclosed |
| US-6103749-A | PHENYL IMIDAZOLE COMPOUNDS USEFUL FOR TREATMENT OF ASTHMA, ALLERGIES, INFLAMMATION AND DEPRESSION | EURO-CELTIQUE S.A. (LU) | 2000-08-15 | — | — | US | disclosed |
| US-5922751-A | BRONCHODILATOR AND ANTIINFLAMMATORY AGENT WITHOUT UNDESIRABLE CARDIOVASCULAR STIMULATION CAUSED BY PHOSPHODIESTERASE III INHIBITOR | EURO-CELTIQUE, S.A. (LU) | 1999-07-13 | — | — | US | disclosed |