Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL6705593 | 0.85 | POLB (0.34) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL15802757 | 0.79 | THRB (0.46) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL15802773 | 0.78 | THRB (0.45) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL1946794 | 0.76 | KMT2A (0.38) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL2375389 | 0.76 | KMT2A (0.38) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL20925765 | 0.76 | THRB (0.40) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL15475367 | 0.74 | THRB (0.44) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL15802677 | 0.74 | TSHR (0.50) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL6142874 | 0.73 | THRB (0.74) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL15636 | 0.73 | THRB (0.74) | THRBTSHRPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777697-B1 | CURABLE SILICONE SEALANT/ADHESIVE COMPOSITIONS | LOCTITE CORP (US) | 2001-09-19 | — | — | EP | claimed |
| US-5605999-A | SEALANT; HIGH STRENGTH, HEAT RESISTANCE; BLEND OF (UNSATURATED)ORGANOSILICON COMPOUND, (METH)ACRYLATE MONOMER AND PROMOTER | LOCTITE CORPORATION (US) | 1997-02-25 | — | — | US | claimed |
| EP-0777697-B1 | CURABLE SILICONE SEALANT/ADHESIVE COMPOSITIONS | LOCTITE CORP (US) | 2001-09-19 | — | — | EP | disclosed |
| EP-0987306-A2 | Curable silicon sealant/adhesive compositions. | LOCTITE CORPORATION (US) | 2000-03-22 | — | — | EP | disclosed |
| EP-0777697-A4 | CURABLE SILICONE SEALANT/ADHESIVE COMPOSITIONS | LOCTITE CORP (US) | 1998-08-19 | — | — | EP | disclosed |
| EP-0777697-A1 | CURABLE SILICONE SEALANT/ADHESIVE COMPOSITIONS | LOCTITE CORPORATION (US) | 1997-06-11 | — | — | EP | disclosed |
| US-5605999-A | SEALANT; HIGH STRENGTH, HEAT RESISTANCE; BLEND OF (UNSATURATED)ORGANOSILICON COMPOUND, (METH)ACRYLATE MONOMER AND PROMOTER | LOCTITE CORPORATION (US) | 1997-02-25 | — | — | US | disclosed |
| WO-1996039458-A1 | CURABLE SILICONE SEALANT/ADHESIVE COMPOSITIONS | LOCTITE CORPORATION (US) | 1996-12-12 | — | — | WO | disclosed |