Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.86 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | MELK | Q14680 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.46 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1535 | 0.93 | ENPP2 (1.00) | ENPP2GAAPKMLMNAPTGS2 | |
| SCHEMBL124022 | 0.87 | GAA (0.67) | ENPP2GAAPKMLMNARAPGEF4 | |
| SCHEMBL18838 | 0.87 | GAA (0.67) | ENPP2GAAPKMLMNARAPGEF4 | |
| SCHEMBL29724901 | 0.87 | GAA (0.67) | ENPP2GAAPKMLMNARAPGEF4 | |
| SCHEMBL3792342 | 0.87 | GAA (0.67) | ENPP2GAAPKMLMNARAPGEF4 | |
| SCHEMBL17548700 | 0.87 | ENPP2 (0.62) | ENPP2GAAPKMLMNAPTGS2 | |
| SCHEMBL388018 | 0.86 | ENPP2 (0.86) | ENPP2LMNAPTGS2CA2CA12 | |
| SCHEMBL11699158 | 0.85 | GAA (0.64) | ENPP2GAAPKMLMNARAPGEF4 | |
| SCHEMBL7938040 | 0.85 | GAA (0.64) | ENPP2GAAPKMLMNARAPGEF4 | |
| Water SCHEMBL6425932 | 0.85 | GAA (0.64) | ENPP2GAAPKMLMNARAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |