Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937961 | 0.87 | GAA (0.39) | MAOBAPP | |
| SCHEMBL7929139 | 0.82 | SLC6A4 (0.50) | LMNAMAPK1CASP3SENP7SENP6 | |
| SCHEMBL7937281 | 0.81 | SOS1 (0.44) | LMNAL3MBTL1KMT2ALTA4HEPHX2 | |
| SCHEMBL7937974 | 0.81 | NPC1 (0.36) | L3MBTL1MAOBAGXT | |
| SCHEMBL7929131 | 0.80 | ESR1 (0.56) | LMNAKMT2AAPPIDO1ELANE | |
| SCHEMBL7935587 | 0.76 | CHRNA7 (0.42) | LMNAMAPK1L3MBTL1KMT2A | |
| SCHEMBL10712854 | 0.75 | MEN1 (0.34) | MAPK1L3MBTL1KMT2AEPHX2 | |
| SCHEMBL16561361 | 0.75 | IDO1 (0.58) | LMNAMAOBIDO1AGXTLOXL2 | |
| SCHEMBL1468357 | 0.75 | IDO1 (0.58) | LMNAMAOBIDO1AGXTLOXL2 | |
| SCHEMBL7929138 | 0.74 | HPGD (0.35) | LMNAMAPK1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |