Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937961 | 0.93 | GAA (0.39) | SOS1HSPB1GAA | |
| SCHEMBL7937974 | 0.86 | NPC1 (0.36) | SCN4AGAAL3MBTL1 | |
| SCHEMBL29375733 | 0.83 | SOS1 (0.56) | SOS1HSPB1SCN4ALTA4HEPHX2 | |
| SCHEMBL7940685 | 0.81 | LMNA (0.41) | LTA4HEPHX2KMT2AL3MBTL1LMNA | |
| SCHEMBL7935587 | 0.81 | CHRNA7 (0.42) | GAAMEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL10712854 | 0.80 | MEN1 (0.34) | EPHX2PPARAMEN1KMT2AKDM4E | |
| SCHEMBL6289867 | 0.80 | SOS1 (0.58) | SOS1HSPB1SCN4ALTA4HEPHX2 | |
| SCHEMBL6290683 | 0.80 | SOS1 (0.58) | SOS1HSPB1SCN4ALTA4HEPHX2 | |
| SCHEMBL351854 | 0.80 | SOS1 (0.58) | SOS1HSPB1SCN4ALTA4HEPHX2 | |
| SCHEMBL7929138 | 0.79 | HPGD (0.35) | GAAPPARAMEN1KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |