SCHEMBL7940725

SCHEMBL7940725

CC(C)CN(C(=O)C(C)C)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CA1 P00915 2/20 0.37
CA12 O43570 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
MLYCD O95822 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18597159 0.79 CA12 (0.32) CA1CA12CA2CA9
SCHEMBL5209106 0.79 CA1 (0.38) CA1CA12CA2CA9MLYCD
SCHEMBL12086283 0.79 KDM4E (0.39) KDM4ETSHRHSD17B10MLYCD
SCHEMBL17471273 0.78 CYP1A2 (0.32) CA1CA12CA2CA9
SCHEMBL5209096 0.77 CA1 (0.37) CA1CA12CA2CA9MLYCD
SCHEMBL5204671 0.74 CA1 (0.34) CA1CA12CA2CA9
SCHEMBL22058879 0.74 KDM4E (0.36) KDM4ETSHRHSD17B10
SCHEMBL20170366 0.74 CA12 (0.34) CA1CA12CA2CA9
SCHEMBL14417164 0.72 KDM4E (0.35) KDM4ETSHRHSD17B10MLYCD
SCHEMBL20924899 0.71 CA12 (0.32) CA1CA12CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6248885-B1 1. TERT-OCTYLDI-N-PROPLYLAMINE. 2. TERT-OCTYL-N-MORPHOLINE-BORANE. SIGMA-ALDRICH CO. 2001-06-19 US disclosed