SCHEMBL7940834

SCHEMBL7940834

Fc1cc(F)c(F)c(-c2c(C(F)(F)F)c(F)c(F)c(F)c2C(F)(F)F)c1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6282031 0.78 CES2 (0.39) CES2CES1
SCHEMBL4218653 0.70 DAO (0.36) CES2CES1
SCHEMBL7944521 0.69 CES2 (0.30) CES2CES1
SCHEMBL6284264 0.69 CES2 (0.33) CES2CES1
SCHEMBL6285468 0.69 CES2 (0.33) CES2CES1
SCHEMBL23108830 0.67 TSHR (0.31)
SCHEMBL13811556 0.67 TSHR (0.31)
SCHEMBL19720191 0.67 CES2 (0.34) CES2CES1
SCHEMBL9507060 0.66 CA1 (0.32)
SCHEMBL6440511 0.65 TSHR (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6248265-B1 Clean generation of a fluoroaryl grignard reagent ALBEMARLE CORPORATION 2001-06-19 US disclosed