Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937693 | 0.88 | MEN1 (0.41) | MAPTMEN1KMT2AKCNH2RXFP1 | |
| SCHEMBL6698829 | 0.83 | MAPT (0.58) | MAPTMEN1KMT2ATP53POLB | |
| SCHEMBL6699427 | 0.81 | MAPT (0.60) | MAPTMEN1KMT2ATP53POLB | |
| SCHEMBL7941009 | 0.80 | MAPT (0.55) | MAPTMEN1KMT2ATP53POLB | |
| SCHEMBL7842626 | 0.76 | MAPT (0.68) | MAPTMEN1KMT2ATP53POLB | |
| SCHEMBL6814897 | 0.76 | MAPT (0.68) | MAPTMEN1KMT2ATP53POLB | |
| SCHEMBL6699753 | 0.76 | MAPT (0.54) | MAPTMEN1KMT2ATP53POLB | |
| SCHEMBL7938457 | 0.76 | MAPT (0.67) | MAPTMEN1KMT2ATP53POLB | |
| SCHEMBL6694734 | 0.73 | MAPT (0.64) | MAPTMEN1KMT2ATP53POLB | |
| SCHEMBL6672864 | 0.73 | MAPT (0.64) | MAPTMEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248739-B1 | DNA POLYMERASE INHIBITORS EFFECTIVE AGAINST HERPESVIRUSES | PHARMACIA & UPJOHN COMPANY | 2001-06-19 | — | — | US | disclosed |