Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | RGS12 | O14924 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7492151 | 1.00 | GAA (0.55) | GAAL3MBTL1ADRA2CKDM4EHIF1A | |
| SCHEMBL4380710 | 0.80 | GAA (0.59) | GAAL3MBTL1ADRA2CKDM4EHIF1A | |
| SCHEMBL20144686 | 0.80 | GAA (0.64) | GAAL3MBTL1ADRA2CKDM4EHIF1A | |
| SCHEMBL5680194 | 0.80 | IDO1 (0.47) | GAAL3MBTL1ADRA2CKDM4EHIF1A | |
| SCHEMBL20144709 | 0.79 | GAA (0.62) | GAAL3MBTL1ADRA2CKDM4EHIF1A | |
| SCHEMBL6704159 | 0.78 | IDO1 (0.50) | GAAL3MBTL1ADRA2CKDM4ELMNA | |
| SCHEMBL16191370 | 0.76 | GAA (0.58) | GAAL3MBTL1LMNAALDH1A1CYP3A4 | |
| SCHEMBL5372125 | 0.76 | GAA (0.49) | GAAL3MBTL1KDM4EHIF1ALMNA | |
| SCHEMBL8705439 | 0.75 | KDM4E (0.53) | GAAL3MBTL1KDM4EHIF1ALMNA | |
| SCHEMBL3310267 | 0.75 | CYP1A2 (0.53) | L3MBTL1KDM4EHIF1ALMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265434-B1 | ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |
| US-6248755-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS; AUTOIMMUNE DISEASES | MERCK & CO., INC. | 2001-06-19 | — | — | US | disclosed |