Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | RGS12 | O14924 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20144686 | 0.98 | GAA (0.64) | GAAL3MBTL1CYP3A4CYP2C19TSHR | |
| SCHEMBL4380710 | 0.95 | GAA (0.59) | GAAL3MBTL1CYP3A4CYP2C19TSHR | |
| SCHEMBL11289322 | 0.80 | LMNA (0.48) | GAAL3MBTL1CYP3A4CYP2C19TSHR | |
| SCHEMBL11035989 | 0.80 | GAA (0.62) | GAAL3MBTL1CYP3A4CYP2C19TSHR | |
| SCHEMBL7941232 | 0.79 | GAA (0.55) | GAAL3MBTL1CYP3A4CYP2C19TSHR | |
| SCHEMBL7492151 | 0.79 | GAA (0.55) | GAAL3MBTL1CYP3A4CYP2C19TSHR | |
| SCHEMBL3671016 | 0.79 | GAA (0.96) | GAAL3MBTL1CYP3A4CYP2C19TSHR | |
| SCHEMBL21104687 | 0.79 | GAA (0.96) | GAAL3MBTL1CYP3A4CYP2C19TSHR | |
| SCHEMBL3665297 | 0.79 | GAA (0.96) | GAAL3MBTL1CYP3A4CYP2C19TSHR | |
| SCHEMBL28091017 | 0.79 | GAA (0.96) | GAAL3MBTL1CYP3A4CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448956-B1 | SOLID PHASE PEPTIDE SYNTHESIS OF PEPTIDE ALCOHOLS | CENTRE NAT RECH SCIENT (FR) | 2018-05-16 | — | — | EP | disclosed |