Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 7/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028674 | 0.90 | IAPP (0.41) | IAPPATMCA2HSPA5 | |
| SCHEMBL8028695 | 0.90 | HSP90AA1 (0.41) | IAPPHSP90AA1HSP90AB1GAAKMT2A | |
| SCHEMBL7942948 | 0.80 | GAA (0.50) | GAAKMT2AATM | |
| SCHEMBL7942438 | 0.78 | IAPP (0.40) | IAPPHSP90AA1HSP90AB1KMT2AATM | |
| SCHEMBL7944834 | 0.78 | IAPP (0.40) | IAPPGAAKMT2AATMCA2 | |
| SCHEMBL7944806 | 0.78 | HSP90AA1 (0.43) | IAPPHSP90AA1HSP90AB1GAAKMT2A | |
| SCHEMBL7944867 | 0.78 | HSP90AA1 (0.40) | IAPPHSP90AA1HSP90AB1GAAKMT2A | |
| SCHEMBL7933554 | 0.77 | HSP90AA1 (0.41) | IAPPHSP90AA1HSP90AB1GAAKMT2A | |
| SCHEMBL7943164 | 0.77 | CA2 (0.41) | IAPPGAAKMT2AATMCA2 | |
| SCHEMBL7942295 | 0.77 | HSPA5 (0.48) | GAAKMT2AATMCA2HSPA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |