Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.47 |
| ▸ | SQLE | Q14534 | 4/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10733007 | 1.00 | KMT2A (0.52) | KMT2AALOX15MAPTALDH1A1MEN1 | |
| SCHEMBL10729108 | 1.00 | KMT2A (0.52) | KMT2AALOX15MAPTALDH1A1MEN1 | |
| SCHEMBL10733011 | 1.00 | KMT2A (0.52) | KMT2AALOX15MAPTALDH1A1MEN1 | |
| SCHEMBL7941569 | 1.00 | KMT2A (0.52) | KMT2AALOX15MAPTALDH1A1MEN1 | |
| SCHEMBL10729116 | 1.00 | KMT2A (0.52) | KMT2AALOX15MAPTALDH1A1MEN1 | |
| SCHEMBL19296596 | 0.89 | ALOX15 (0.55) | ALOX15ALDH1A1 | |
| SCHEMBL114337 | 0.89 | ALOX15 (0.55) | ALOX15ALDH1A1 | |
| SCHEMBL18316483 | 0.89 | ALOX15 (0.55) | ALOX15ALDH1A1 | |
| SCHEMBL13279733 | 0.89 | ALOX15 (0.55) | ALOX15ALDH1A1 | |
| SCHEMBL11250650 | 0.85 | KMT2A (0.50) | KMT2AALOX15MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288128-B1 | β,γ-dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound | EISAI CO., LTD. (JP) | 2001-09-11 | — | — | US | disclosed |
| US-5280048-A | Antiinfection agent | EISAI CO., LTD. (JP) | 1994-01-18 | — | — | US | disclosed |
| US-4624966-A | β,γ-dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound | EISAI CO., LTD. (JP) | 1986-11-25 | — | — | US | disclosed |