Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27853702 | 0.75 | ALDH1A1 (0.38) | ALDH1A1TP53TSHRGLAKDM4E | |
| SCHEMBL6156404 | 0.71 | ALDH1A1 (0.40) | ALDH1A1LMNATP53SMN1; SMN2TSHR | |
| SCHEMBL3239379 | 0.71 | ALDH1A1 (0.40) | ALDH1A1LMNATP53SMN1; SMN2GLA | |
| SCHEMBL3241706 | 0.71 | ESR1 (0.46) | ALDH1A1LMNATP53SMN1; SMN2TSHR | |
| SCHEMBL19565725 | 0.71 | ALDH1A1 (0.40) | ALDH1A1LMNATP53SMN1; SMN2TSHR | |
| SCHEMBL8754925 | 0.67 | ALDH1A1 (0.51) | ALDH1A1LMNATP53SMN1; SMN2TSHR | |
| SCHEMBL11704619 | 0.65 | TSHR (0.48) | ALDH1A1TP53TSHRGLAKDM4E | |
| SCHEMBL2398343 | 0.64 | TAAR1 (0.47) | ALDH1A1LMNATP53SMN1; SMN2TSHR | |
| SCHEMBL6399613 | 0.63 | ALDH1A1 (0.44) | ALDH1A1LMNATP53SMN1; SMN2TSHR | |
| SCHEMBL20831313 | 0.63 | NPSR1 (0.47) | ALDH1A1LMNAKDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242002-B1 | RAPIDLY DISINTEGRATING ORAL DOSAGE FORM OF ALKALI-SENSITIVE MATERIAL, EFFERVESCENT BASE OF ALKALINE EARTH METAL CARBONATE, ORGANIC EDIBLE ACID AND ALKALI METAL SALT OF CITRIC ACID, AUXILIARY INGREDIENTS | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2001-06-05 | — | — | US | disclosed |