SCHEMBL7941692

SCHEMBL7941692

CCS(=O)(=O)CC.O=C1c2c(F)c(F)c(F)c(F)c2C(=O)N1c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA1A P0DMV8 1/20 0.41
PABPC1 P11940 1/20 0.41
ELANE P08246 3/20 0.41
ALDH1A1 P00352 4/20 0.39
POLB P06746 1/20 0.39
DPP8 Q6V1X1 1/20 0.39
HSD17B10 Q99714 2/20 0.38
ANPEP P15144 1/20 0.38
DPP4 P27487 1/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
CASP1 P29466 1/20 0.38
CASP3 P42574 1/20 0.38
CASP7 P55210 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
ALOX15 P16050 1/20 0.38
MAPK1 P28482 1/20 0.38
NPSR1 Q6W5P4 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2550420 0.86 HSPA1A (0.52) HSPA1APABPC1ALDH1A1POLBDPP8
SCHEMBL7938900 0.73 MEN1 (0.32) ALDH1A1HSD17B10HPGDCASP1CASP7
SCHEMBL12748802 0.73 HSPA1A (0.46) HSPA1APABPC1ALDH1A1POLBDPP8
SCHEMBL4547007 0.72 HSP90AA1 (0.57) HSPA1APABPC1ALDH1A1POLBHSD17B10
SCHEMBL2561939 0.72 ELANE (0.54) ELANEALDH1A1HSD17B10ANPEPDPP4
SCHEMBL8846028 0.71 HSPA1A (0.45) HSPA1APABPC1ALDH1A1POLBDPP8
SCHEMBL2557159 0.70 HSP90AA1 (0.56) ALDH1A1HSD17B10ANPEPDPP4MAPK1
SCHEMBL30385072 0.70 ELANE (0.44) ELANEALDH1A1KDM4EMAPK1GAA
SCHEMBL826295 0.70 ELANE (0.44) ELANEALDH1A1KDM4EMAPK1GAA
SCHEMBL27622789 0.70 HSP90AA1 (0.42) HSPA1APABPC1ALDH1A1POLBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6191307-B1 Process for making benzoic acids ALBEMARLE CORPORATION 2001-02-20 US disclosed