Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7940553 | 0.82 | PDE4B (0.55) | ALDH1A1PDE4APDE4BNPC1RAB9A | |
| SCHEMBL7353267 | 0.81 | PDE4A (0.53) | ALDH1A1PDE4APDE4BNPC1RAB9A | |
| SCHEMBL7353160 | 0.80 | PDE4A (0.44) | ALDH1A1PDE4APDE4BNPC1RAB9A | |
| SCHEMBL7441450 | 0.79 | KCNH2 (0.45) | ALDH1A1RAB9AMAPTMAPK1EIF4A1 | |
| SCHEMBL7440932 | 0.78 | PDE4A (0.67) | ALDH1A1PDE4APDE4BNPC1RAB9A | |
| SCHEMBL7355006 | 0.78 | PDE4A (0.50) | ALDH1A1PDE4APDE4BNPC1RAB9A | |
| SCHEMBL7933011 | 0.78 | PDE4B (0.67) | ALDH1A1PDE4APDE4BNPC1RAB9A | |
| SCHEMBL7353625 | 0.78 | PDE4A (0.50) | ALDH1A1PDE4APDE4BNPC1RAB9A | |
| SCHEMBL7446525 | 0.78 | PDE4A (0.66) | ALDH1A1PDE4APDE4BNPC1RAB9A | |
| SCHEMBL7352127 | 0.77 | PDE4A (0.47) | ALDH1A1PDE4APDE4BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834508-B1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-08-16 | — | — | EP | disclosed |
| EP-0834508-A1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-08 | — | — | EP | disclosed |