Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28639759 | 0.84 | TSHR (0.33) | TSHR | |
| SCHEMBL10670316 | 0.83 | — | — | |
| SCHEMBL10606399 | 0.82 | — | — | |
| SCHEMBL9546011 | 0.79 | TSHR (0.37) | TSHR | |
| SCHEMBL1534241 | 0.77 | ALDH1A1 (0.36) | — | |
| SCHEMBL7601813 | 0.76 | TSHR (0.34) | TSHR | |
| SCHEMBL7610154 | 0.76 | — | — | |
| SCHEMBL7597383 | 0.74 | TSHR (0.32) | TSHR | |
| SCHEMBL9956277 | 0.69 | — | — | |
| SCHEMBL27910295 | 0.69 | TSHR (0.55) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5855825-A | POLYSILOXANE-POLYACRYLATE | MENICON CO., LTD. (JP) | 1999-01-05 | — | — | US | claimed |
| US-6255362-B1 | HYDRATED, CROSSLINKED COPOLYACRYLATE CONTAINING SILOXANE, URETHANE AND ETHER GROUPS; CLEAR, DURABLE, FLEXIBLE SOFT CONTACT LENSES | MENICON CO., LTD. (JP) | 2001-07-03 | — | — | US | disclosed |
| WO-1995009878-A1 | POLYMER COMPOSITIONS SUITABLE FOR USE AS CONTACT LENS | PILKINGTON BARNES HIND, INC. (US) | 1995-04-13 | — | — | WO | disclosed |